University of Maryland
USA
The Malaria Section at the University of Maryland's School of Medicine works on malaria drug resistance, molecular epidemiology, molecular evolution, pathogenesis, HIV-malaria interactions and clinical trials of malaria drugs and vaccines. They conduct laboratory and field research on the molecular mechanisms and molecular epidemiology of resistance to antimalarial drugs, particularly the antifolate drugs and chloroquine.
In collaboration with colleagues at the University of Mali, the team at the Malaria Section have developed a field research site in the Dogon Country of Mali. This field station is the site of studies of drug resistance, pathogenesis and immunology of severe malaria, and clinical trials of malaria vaccines.
In Malawi the team work on clinical trials of malaria drugs, molecular epidemiology of drug-resistant malaria and the impact of antimicrobial use on antimalarial drug resistance in people living with HIV. At the Center for Vaccine Development in Baltimore, they study the impact of genetic diversity on malaria drug and vaccine efficacy using high-throughput genotyping and mathematical modelling.