Consortial and Community Projects
Malaria involves three genomes, those of the host (human), the parasite (Plasmodium) and the mosquito vector (Anopheles). MalariaGEN provides a platform for malaria researchers around the world to work together on large-scale collaborative projects that combine epidemiology with analysis of genome variation in host, parasite and vector populations.
Host projects
- Genetic resistance to severe malaria (CP1)
- Genetic determinants of the immune response to malaria (CP2)
- Human genome diversity in malaria-endemic regions (CP3)
- Linkage analysis of host resistance to malaria (CP4)
See also the introduction to our work on human genetics.
Parasite projects
- Plasmodium falciparum population genomics
- Plasmodium falciparum genetic crosses
- Plasmodium vivax genome variation
See also the introduction to our work on Plasmodium genetics.
Vector projects
How MalariaGEN projects work
MalariaGEN investigators have established two approaches for collaborative data-sharing: consortial projects and community projects.
Each consortial project or community project is made up of multiple partner studies. There are now over 40 partner studies in more than 20 countries, each led by an independent investigator and with its own scientific objectives.
Consortial projects and community projects add value to partner studies by providing access to genotyping and sequencing technologies, and by providing a framework for sharing and integrating data across different studies.