Publications

Latest publications

12 Oct 2020

Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes

Ford A, Kepple D, Abagero BR, Connors J, Pearson R, Auburn S, Getachew S, Ford C, Gunalan K, Miller LH, Janies DA, Rayner JC, Yan G, Yewhalaw D, Lo E.
PLoS Neglected Tropical Diseases 2020 14(10) e0008234 DOI: 10.1371/journal.pntd.0008234
1 Oct 2020

Evolution of the Insecticide Target Rdl in African Anopheles Is Driven by Interspecific and Interkaryotypic Introgression

Grau-Bové X, Tomlinson S, O'Reilly AO, Harding NJ, Miles A, Kwiatkowski D, Donnelly MJ, Weetman D; Anopheles gambiae 1000 Genomes Consortium.
Mol Biol Evol 2020 1 37 DOI: 10.1093/molbev/msaa128
20 Aug 2020

Antimalarial drug resistance molecular makers of Plasmodium falciparum isolates from Sudan during 2015–2017

Hussien M, Abdel Hamid MM, Elamin EA, Hassan AO, Elaagip AH, Salama AHA, Abdelraheem MH, Mohamed AO.
PLOS ONE 2020 15(8) e0235401 DOI: 10.1371/journal.pone.0235401
20 Aug 2020

Antimalarial drug resistance molecular makers of Plasmodium falciparum isolates from Sudan during 2015–2017

Hussien M, Abdel Hamid MM, Elamin EA, Hassan AO, Elaagip AH, Salama AHA, Abdelraheem MH, Mohamed AO.
PLOS ONE 2020 15(8) e0235401 DOI: 10.1371/journal.pone.0235401
9 Jul 2020

Genetic diversity and neutral selection in Plasmodium vivax erythrocyte binding protein correlates with patient antigenicity

Han JH, Cho JS, Ong JJY, Park JH, Nyunt MH, Sutanto E, Trimarsanto H, Petros B, Aseffa A, Getachew S, Sriprawat K, Anstey NM, Grigg MJ, Barber BE, William T, Qi G, Liu Y, Pearson RD, Auburn S, Price RN, Nosten F, Rénia L, Russell B, Han ET.
PLoS Neglected Tropical Diseases 2020 14(7) e0008202 DOI: 10.1371/journal.pntd.0008202
21 May 2020

Efficacy of dihydroartemisinin/piperaquine and artesunate monotherapy for the treatment of uncomplicated Plasmodium falciparum malaria in Central Vietnam

Rovira-Vallbona E, Van Hong N, Kattenberg JH, Huan RM, Hien NTT, Ngoc NTH, Guetens P, Hieu NL, Mai TT, Duong NTT, Duong TT, Phuc BQ, Xa NX, Erhart A, Rosanas-Urgell A.
Journal of Antimicrobial Chemotherapy 2020 75 2272 DOI: https://doi.org/10.1093/jac/dkaa172
21 May 2020

Efficacy of dihydroartemisinin/piperaquine and artesunate monotherapy for the treatment of uncomplicated Plasmodium falciparum malaria in Central Vietnam

Rovira-Vallbona E, Van Hong N, Kattenberg JH, Huan RM, Hien NTT, Ngoc NTH, Guetens P, Hieu NL, Mai TT, Duong NTT, Duong TT, Phuc BQ, Xa NX, Erhart A, Rosanas-Urgell A.
Journal of Antimicrobial Chemotherapy 2020 75 2272 DOI: https://doi.org/10.1093/jac/dkaa172
4 Mar 2020

Mapping the travel patterns of people with malaria in Bangladesh

Sinha I, Sayeed AA, Uddin D, Wesolowski A, Zaman SI, Faiz MA, Ghose A, Rahman MR, Islam A, Karim MJ, Saha A, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Chang HH, Miotto O, Kwiatkowski D, Dondorp AM, Day NPJ, Hossain MA, Buckee C, Maude RJ.
BMC Medicine 2020 18(1) 45 DOI: 10.1186/s12916-020-1512-5
4 Mar 2020

Mapping the travel patterns of people with malaria in Bangladesh

Sinha I, Sayeed AA, Uddin D, Wesolowski A, Zaman SI, Faiz MA, Ghose A, Rahman MR, Islam A, Karim MJ, Saha A, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Chang HH, Miotto O, Kwiatkowski D, Dondorp AM, Day NPJ, Hossain MA, Buckee C, Maude RJ.
BMC Medicine 2020 18(1) 45 DOI: 10.1186/s12916-020-1512-5
4 Mar 2020

Mapping the travel patterns of people with malaria in Bangladesh

Sinha I, Sayeed AA, Uddin D, Wesolowski A, Zaman SI, Faiz MA, Ghose A, Rahman MR, Islam A, Karim MJ, Saha A, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Chang HH, Miotto O, Kwiatkowski D, Dondorp AM, Day NPJ, Hossain MA, Buckee C, Maude RJ.
BMC Medicine 2020 18(1) 45 DOI: 10.1186/s12916-020-1512-5
1 Mar 2020

Plasmodium vivax Malaria Viewed through the Lens of an Eradicated European Strain

van Dorp L, Gelabert P, Rieux A, de Manuel M, de-Dios T, Gopalakrishnan S, Carøe C, Sandoval-Velasco M, Fregel R, Olalde I, Escosa R, Aranda C, Huijben S, Mueller I, Marquès-Bonet T, Balloux F, Gilbert MTP, Lalueza-Fox C.
Molecular Biology and Evolution 2020 37(3) 773-785 DOI: 10.1093/molbev/msz264
18 Feb 2020

Assessment of Plasmodium falciparum drug resistance molecular markers from the Blue Nile State, Southeast Sudan

Mohamed AO, Hussien M, Mohamed A, Suliman A, Elkando NS, Abdelbagi H, Malik EM, Abdelraheem MH, Hamid MMA.
Malaria Journal 2020 19(1) 78 DOI: 10.1186/s12936-020-03165-0
18 Feb 2020

Assessment of Plasmodium falciparum drug resistance molecular markers from the Blue Nile State, Southeast Sudan

Mohamed AO, Hussien M, Mohamed A, Suliman A, Elkando NS, Abdelbagi H, Malik EM, Abdelraheem MH, Hamid MMA.
Malaria Journal 2020 19(1) 78 DOI: 10.1186/s12936-020-03165-0
13 Feb 2020

A molecular barcode to inform the geographical origin and transmission dynamics of Plasmodium vivax malaria

Diez Benavente E, Campos M, Phelan J, Nolder D, Dombrowski JG, Marinho CRF, Sriprawat K, Taylor AR, Watson J, Roper C, Nosten F, Sutherland CJ, Campino S, Clark TG.
PLoS Genetics 2020 16(2) e1008576 DOI: 10.1371/journal.pgen.1008576
5 Feb 2020

Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials

Phommasone K, van Leth F, Peto TJ, Landier J, Nguyen TN, Tripura R, Pongvongsa T, Lwin KM, Kajeechiwa L, Thwin MM, Parker DM, Wiladphaingern J, Nosten S, Proux S, Nguon C, Davoeung C, Rekol H, Adhikari B, Promnarate C, Chotivanich K, Hanboonkunupakarn B, Jittmala P, Cheah PY, Dhorda M, Imwong M, Mukaka M, Peerawaranun P, Pukrittayakamee S, Newton PN, Thwaites GE, Day NPJ, Mayxay M, Hien TT, Nosten FH, Cobelens F, Dondorp AM, White NJ, von Seidlein L.
PloS One 2020 15 e0228190 DOI: 10.1371/journal.pone.0228190
18 Dec 2019

Intracluster correlation coefficients in the Greater Mekong Subregion for sample size calculations of cluster randomized malaria trials

Peerawaranun P, Landier J, Nosten FH, Nguyen TN, Hien TT, Tripura R, Peto TJ, Phommasone K, Mayxay M, Day NPJ, Dondorp A, White N, von Seidlein L, Mukaka M.
Intracluster correlation coefficients in the Greater Mekong Subregion for sample size calculations of cluster randomized malaria trials 2019 18 428 DOI: 10.1186/s12936-019-3062-x
24 Sep 2019

A molecular barcode and online tool to identify and map imported infection with Plasmodium vivax

Hidayat Trimarsanto, Roberto Amato, Richard D Pearson, Edwin Sutanto, Rintis Noviyanti, Leily Trianty, Jutta Marfurt, Zuleima Pava, Diego F Echeverry, Tatiana M Lopera-Mesa, Lidia Madeline Montenegro, Alberto Tobón-Castaño, Matthew J Grigg, Bridget Barber, Timothy William, Nicholas M Anstey, Sisay Getachew, Beyene Petros, Abraham Aseffa, Ashenafi Assefa, Awab Ghulam Rahim, Nguyen Hoang Chau, Tran Tinh Hien, Mohammad Shafiul Alam, Wasif A Khan, Benedikt Ley, Kamala Thriemer, Sonam Wangchuck, Yaghoob Hamedi, Ishag Adam, Yaobao Liu, Qi Gao, Kanlaya Sriprawat, Marcelo U Ferreira, Alyssa Barry, Ivo Mueller, Eleanor Drury, Sonia Goncalves, Victoria Simpson, Olivo Miotto, Alistair Miles, Nicholas J White, Francois Nosten, Dominic P Kwiatkowski, Ric N Price, Sarah Auburn
bioRxiv 2019 776781 DOI: https://doi.org/10.1101/776781
2 Apr 2019

Mapping imported malaria in Bangladesh using parasite genetic and human mobility data

Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A, Uddin D, Zaman SI, Hossain MA, Faiz MA, Ghose A, Sayeed AA, Rahman MR, Islam A, Karim MJ, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Drury E, Gonçalves S, Kekre M, Dhorda M, Vongpromek R, Miotto O, Engø-Monsen K, Kwiatkowski D, Maude RJ, Buckee C
eLife 2019 8 e43481 DOI: https://doi.org/10.7554/eLife.43481
2 Apr 2019

Mapping imported malaria in Bangladesh using parasite genetic and human mobility data

Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A, Uddin D, Zaman SI, Hossain MA, Faiz MA, Ghose A, Sayeed AA, Rahman MR, Islam A, Karim MJ, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Drury E, Gonçalves S, Kekre M, Dhorda M, Vongpromek R, Miotto O, Engø-Monsen K, Kwiatkowski D, Maude RJ, Buckee C
eLife 2019 8 e43481 DOI: https://doi.org/10.7554/eLife.43481
2 Apr 2019

Mapping imported malaria in Bangladesh using parasite genetic and human mobility data

Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A, Uddin D, Zaman SI, Hossain MA, Faiz MA, Ghose A, Sayeed AA, Rahman MR, Islam A, Karim MJ, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Drury E, Gonçalves S, Kekre M, Dhorda M, Vongpromek R, Miotto O, Engø-Monsen K, Kwiatkowski D, Maude RJ, Buckee C
eLife 2019 8 e43481 DOI: https://doi.org/10.7554/eLife.43481
15 Feb 2019

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial

von Seidlein L, Peto TJ, Landier J, Nguyen TN, Tripura R, Phommasone K, Pongvongsa T, Lwin KM, Keereecharoen L, Kajeechiwa L, Thwin MM, Parker DM, Wiladphaingern J, Nosten S, Proux S, Corbel V, Tuong-Vy N, Phuc-Nhi TL, Son DH, Huong-Thu PN, Tuyen NTK, Tien NT, Dong LT, Hue DV, Quang HH, Nguon C, Davoeung C, Rekol H, Adhikari B, Henriques G, Phongmany P, Suangkanarat P, Jeeyapant A, Vihokhern B, van der Pluijm RW, Lubell Y, White LJ, Aguas R, Promnarate C, Sirithiranont P, Malleret B, Rénia L, Onsjö C, Chan XH, Chalk J, Miotto O, Patumrat K, Chotivanich K, Hanboonkunupakarn B, Jittmala P, Kaehler N, Cheah PY, Pell C, Dhorda M, Imwong M, Snounou G, Mukaka M, Peerawaranun P, Lee SJ, Simpson JA, Pukrittayakamee S, Singhasivanon P, Grobusch MP, Cobelens F, Smithuis F, Newton PN, Thwaites GE, Day NPJ, Mayxay M, Hien TT, Nosten FH, Dondorp AM, White NJ.
PLOS Medicine 2019 16 e1002745 DOI: 10.1371/journal.pmed.1002745
24 Jan 2019

Access to and use of preventive intermittent treatment for Malaria during pregnancy: A qualitative study in the Chókwè district, Southern Mozambique

Arnaldo P, Cambe MI, Magaço A, Chicumbe S, Rovira-Vallbona E, Rosanas-Urgell A, Enosse SM.
PLoS One 2019 14 e0203740 DOI: 10.1371/journal.pone.0203740
21 Jan 2019

Genomic analysis of Plasmodium vivax in southern Ethiopia reveals selective pressures in multiple parasite mechanisms.

Auburn S, Getachew S, Pearson RD, Amato R, Miotto O, Trimarsanto H, Zhu SJ, Rumaseb A, Marfurt J, Noviyanti R, Grigg MJ, Barber B, William T, Goncalves SM, Drury E, Sriprawat K, Anstey NM, Nosten F, Petros B, Aseffa A, McVean G, Kwiatkowski DP, Price RN.
The Journal of Infectious Diseases 2019 220 1738-1749 DOI: 10.1093/infdis/jiz016
17 Jan 2019

Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria

Lacerda MVG, Llanos-Cuentas A, Krudsood S, Lon C, Saunders DL, Mohammed R, Yilma D, Batista Pereira D, Espino FEJ, Mia RZ, Chuquiyauri R, Val F, Casapía M, Monteiro WM, Brito MAM, Costa MRF, Buathong N, Noedl H, Diro E, Getie S, Wubie KM, Abdissa A, Zeynudin A, Abebe C, Tada MS, Brand F, Beck HP, Angus B, Duparc S, Kleim JP, Kellam LM, Rousell VM, Jones SW, Hardaker E, Mohamed K, Clover DD, Fletcher K, Breton JJ, Ugwuegbulam CO, Green JA, Koh GCKW.
New England Journal of Medicine 2019 380(3) 215-228 DOI: 10.1056/NEJMoa1710775
17 Jan 2019

Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria

Llanos-Cuentas A, Lacerda MVG, Hien TT, Vélez ID, Namaik-Larp C, Chu CS, Villegas MF, Val F, Monteiro WM, Brito MAM, Costa MRF, Chuquiyauri R, Casapía M, Nguyen CH, Aruachan S, Papwijitsil R, Nosten FH, Bancone G, Angus B, Duparc S, Craig G, Rousell VM, Jones SW, Hardaker E, Clover DD, Kendall L, Mohamed K, Koh GCKW, Wilches VM, Breton JJ, Green JA.
New England Journal of Medicine 2019 380(3) 229-241 DOI: 10.1056/NEJMoa1802537
17 Dec 2018

Host genetic polymorphisms and serological response against malaria in a selected population in Sri Lanka

Dewasurendra RL, Jeffreys A, Gunawardena SA, Chandrasekharan NV, Rockett K, Kwiatkowski D, & Karunaweera ND
Malaria Journal 2018 17 473 DOI: 10.1186/s12936-018-2622-9
4 Dec 2018

The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background

Zhu l, Tripathi J, Rocamora FM, Miotto O, Van der Pluijm R, Voss TS, Mok S, Kwiatkowski DP, Nosten F, Day NPJ, White NJ, Dondorp AM & Bozdech Z.
Nature Communications 2018 9 5158 DOI: 10.1038/s41467-018-07588-x
29 Nov 2018

A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways

Campino S, Marin-Menendez A, Kemp A, Cross N, Drought l, Otto TD, Benavente ED, Ravenhall M, Schwach F, Girling G, Manske M, Theron M, Gould K, Drury E, Clark TG, Kwiatkowski DP, Pance A & Rayner JC.
PLoS Pathogens 2018 4(11) DOI: https://doi.org/10.1371/journal.ppat.1007436
26 Nov 2018

Lack of significant recovery of chloroquine sensitivity in Plasmodium falciparum parasites following discontinuance of chloroquine use in Papua New Guinea

Sekihara M, Tachibana SI, Yamauchi M, Yatsushiro S, Tiwara S, Fukuda N, Ikeda M, Mori T, Hirai M, Hombhanje F, Mita T.
Malaria Journal 2018 17 434 DOI: https://doi.org/10.1186/s12936-018-2585-x
25 Oct 2018

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development

Duffy CW, Amambua-Ngwa A, Ahouidi AD, Diakite M, Awandare GA, Ba H, Tarr SJ, Murray l, Stewart lB, D'Alessandro U, Otto TD, Kwiatkowski DP & Conway DJ.
Scientific Reports 2018 8 15763 DOI: 10.1038/s41598-018-34078-3