Publications
Featured publications
16 Jan 2023
Pf7: An open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples
Wellcome Open Research 2023 8 22 DOI: https://doi.org/10.12688/wellcomeopenres.18681.18 Apr 2022
An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
Wellcome Open Research 2022 7 136 DOI: https://doi.org/10.12688/wellcomeopenres.17795.124 Feb 2021
An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples
Wellcome Open Research 2021 6 42 DOI: 10.12688/wellcomeopenres.16168.128 Sep 2020
Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii
Genome Research 2020 30 1533-1546 DOI: 10.1101/gr.262790.12016 Dec 2019
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
Nature Communications 2019 10 5732 DOI: 10.1038/s41467-019-13480-z1 Feb 2018
Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study
The Lancet Infectious Diseases 2018 18 337-345 DOI: 10.1016/S1473-3099(18)30068-929 Nov 2017
Genetic diversity of the African malaria vector Anopheles gambiae
Nature 2017 DOI: 10.1038/nature2499527 Jun 2016
Genomic analysis of local variation and recent evolution in Plasmodium vivax
Nature Genetics 2016 48 959-964 DOI: 10.1038/ng.359911 Dec 2008
A global network for investigating the genomic epidemiology of malaria
Nature 2008 456(7223) 732-7 DOI: 10.1038/nature07632Latest publications
19 Jul 2018
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
The Lancet Haematology 2018 5 DOI: 10.1016/S2352-3026(18)30107-826 Jun 2018
Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia
Scientific Reports 2018 8 9687 DOI: 10.1038/s41598-018-28017-517 May 2018
Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics
Nature Communications 2018 9 2585 DOI: 10.1038/s41467-018-04965-425 Apr 2018
Two complement receptor one alleles have opposing associations with cerebral malaria and interact with alpha(+)thalassaemia
eLife 2018 7 DOI: 10.7554/eLife.3157912 Mar 2018
Uptake of intermittent preventive treatment and pregnancy outcomes: health facilities and community surveys in Chókwè district, southern Mozambique
Malaria Journal 2018 17 109 DOI: 10.1186/s12936-018-2255-z7 Nov 2017
Molecular markers for artemisinin and partner drug resistance in natural Plasmodium falciparum populations following increased insecticide treated net coverage along the slope of mount Cameroon: cross-sectional study
Infectious Diseases of Poverty 2017 6 136 DOI: 10.1186/s40249-017-0350-y6 Sep 2017
Safety and effectiveness of mass drug administration to accelerate elimination of artemisinin-resistant falciparum malaria: A pilot trial in four villages of Eastern Myanmar
Wellcome Open Research 2017 2 81 DOI: https://doi.org/10.12688/wellcomeopenres.12240.122 Aug 2017
Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data
Bioinformatics 2017 DOI: 10.1093/bioinformatics/btx53023 Jun 2017
Panoptes: web-based exploration of large scale genome variation data
Bioinformatics 2017 DOI: 10.1093/bioinformatics/btx4107 Jun 2017
Evidence from a natural experiment that malaria parasitemia is pathogenic in retinopathy-negative cerebral malaria
eLife 2017 6 e2369 DOI: 10.7554/eLife.2369925 May 2017
Malaria host candidate genes validated by association with current, recent and historic measures of transmission intensity
The Journal of Infectious Diseases 2017 DOI: 10.1093/infdis/jix25019 May 2017
Resistance to malaria through structural variation of red blood cell invasion receptors
Science 2017 DOI: 10.1126/science.aam639319 May 2017
Resistance to malaria through structural variation of red blood cell invasion receptors
Science 2017 DOI: 10.1126/science.aam639311 May 2017
Genomic variation in Plasmodium vivax malaria reveals regions under selective pressure
PLoS One 2017 12(5) e0177134 DOI: 10.1371/journal.pone.017713415 Mar 2017
Population genetic structure and adaptation of malaria parasites on the edge of endemic distribution
Molecular Ecology 2017 DOI: 10.1111/mec.1406626 Jan 2017
THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites
PLoS Computational Biology 2017 13(1) e1005348 DOI: 10.1371/journal.pcbi.100534825 Jan 2017
Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution
Nature 2017 DOI: 10.1038/nature2103824 Jan 2017
Culture adaptation of malaria parasites selects for convergent loss-of-function mutants
Scientific Reports 2017 7 41303 DOI: 10.1038/srep413039 Jan 2017
Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia
eLife 2017 6 e15085 DOI: 10.7554/eLife.1508520 Dec 2016
Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification
Malaria Journal 2016 15 597 DOI: 10.1186/s12936-016-1641-720 Dec 2016
Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification
Malaria Journal 2016 15 597 DOI: 10.1186/s12936-016-1641-719 Dec 2016
Extreme mutation bias and high AT content in Plasmodium falciparum
Nucleic Acids Research 2016 pii gkw1259 DOI: 10.1093/nar/gkw125915 Nov 2016
A new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genes
Wellcome Open Research 2016 1 4 DOI: 10.12688/wellcomeopenres.9876.13 Nov 2016
Genetic markers associated with dihydroartemisinin–piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype–phenotype association study
The Lancet Infectious Diseases 2016 DOI: 10.1016/S1473-3099(16)30409-115 Oct 2016
Genomic analysis reveals a common breakpoint in amplifications of the Plasmodium vivax multidrug resistance 1 locus in Thailand
The Journal of Infectious Diseases 2016 214 1235-1242 DOI: 10.1093/infdis/jiw32314 Oct 2016
Independent origin and global distribution of distinct Plasmodium vivax Duffy Binding Protein gene duplications
PLoS Neglected Tropical Diseases 2016 10(10) e0005091 DOI: 10.1371/journal.pntd.000509116 Aug 2016
Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum
Genome Research 2016 26 1288-1299 DOI: 10.1101/gr.203711.115.21 Jun 2016
Admixture into and within sub-Saharan Africa
eLife 2016 5:e15266 DOI: 10.7554/eLife.1526624 Mar 2016
Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: implications for prevention, treatment and elimination strategies
Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: implications for prevention, treatment and elimination strategies 2016 15 181 DOI: 10.1186/s12936-016-1224-78 Mar 2016