1097 Detection of artemisinin-resistant Plasmodium falciparum parasites in Southern Mali

Projects:

P. falciparum Community Project

Locations: Mali (ML)

Partner study description

Abdoulaye Djimdé at the Malaria Research and Training Centre at the University of Bamako and Oumou Maïga-Ascofaré are investigating the genetic signature of drug pressure on Plasmodium falciparum parasites collected in a seasonal transmission areas in Southern Mali. Samples collected before and after the introduction of artemisinin-based combination therapy (ACT) are compared for signatures of a recent positive selection. This study is contributing to the Plasmodium Diversity Network Africa (PDNA), an African-led network investigating the genetic diversity and drug resistance of Plasmodium parasites across Africa.

Key People

Prof Abdoulaye Djimdé
Associate Professor of Parasitology and Mycology; Chief of the Molecular Epidemiology and Drug Resistance Unit
Malaria Research and Training Centre, University of Science, Techniques and Technologies of Bamako, Mali
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Dr Oumou Maïga-Ascofaré
Research Fellow
Bernhard Nocht Institute for Tropical Medicine, Germany
Research Fellow
Research in Tropical Medicine, Kwame Nkrumah University of Sciences and Technology, Kumasi, Ghana
Associate Scientist
Malaria Research and Training Centre, University of Science, Techniques and Technologies of Bamako, Mali
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