Over 50 publications have analysed data from this and previous versions of the MalariaGEN P. falciparum data resource.

Citation for this data resource

A paper describing the Pf7 data release is in preparation. To reference the MalariaGEN P. falciparum data resource please cite our publication about the Pf6 data release:

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

Featured publications

Key methodological or multisite publications from MalariaGEN, partners, and community members contributing to or using data releases.

Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study

Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study

Genetic surveillance in the Greater Mekong Subregion and South Asia to support malaria control and elimination

Genomic structure and diversity of Plasmodium falciparum in Southeast Asia reveal recent parasite migration patterns

Major subpopulations of Plasmodium falciparum in sub-Saharan Africa

Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study

Latest publications

Publications from MalariaGEN, partners, and community members related to data, analyses, or methods for Plasmodium data releases.

Access to and use of preventive intermittent treatment for Malaria during pregnancy: A qualitative study in the Chókwè district, Southern Mozambique

A comprehensive analysis of drug resistance molecular markers and Plasmodium falciparum genetic diversity in two malaria endemic sites in Mali

A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya.

A microarray platform and novel SNP calling algorithm to evaluate Plasmodium falciparum field samples of low DNA quantity

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing

Antimalarial drug resistance molecular makers of Plasmodium falciparum isolates from Sudan during 2015–2017

Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

Assessment of Plasmodium falciparum drug resistance molecular markers from the Blue Nile State, Southeast Sudan

Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants

Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection

Characterization of putative drug resistant biomarkers in Plasmodium falciparum isolated from Ghanaian blood donors

Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity

Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia

Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data

Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients

Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens

estMOI: estimating multiplicity of infection using parasite deep sequencing data

Evaluating 18s-rRNA LAMP and selective whole genome amplification (sWGA) assay in detecting asymptomatic Plasmodium falciparum infections in blood donors

Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers

Genetic architecture of artemisinin-resistant Plasmodium falciparum

Genetic diversity of next generation antimalarial targets: A baseline for drug resistance surveillance programmes

Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia

Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study

Genome-wide analysis of selection on the malaria parasite Plasmodium falciparum in West African populations of differing infection endemicity

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

Genomic analysis of local variation and recent evolution in Plasmodium vivax

Global analysis of Plasmodium falciparum histidine-rich protein-2 (pfhrp2) and pfhrp3 gene deletions using whole-genome sequencing data and meta-analysis

Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development

hmmIBD: software to infer pairwise identity by descent between haploid genotypes

Identity-by-descent analyses for measuring population dynamics and selection in recombining pathogens

Imputation-Based Population Genetics Analysis of Plasmodium falciparum Malaria Parasites

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia

Inferring Strain Mixture within Clinical Plasmodium falciparum Isolates from Genomic Sequence Data

K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa

Major subpopulations of Plasmodium falciparum in sub-Saharan Africa

Microsatellite genotyping and genome-wide single nucleotide polymorphism-based indices of Plasmodium falciparum diversity within clinical infections

Molecular markers for artemisinin and partner drug resistance in natural Plasmodium falciparum populations following increased insecticide treated net coverage along the slope of mount Cameroon: cross-sectional study

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development

Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study

Panoptes: web-based exploration of large scale genome variation data

Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro

Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay

Population genetic analysis of the Plasmodium falciparum circumsporozoite protein in two distinct ecological regions in Ghana

Population genetic structure and adaptation of malaria parasites on the edge of endemic distribution

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

Spatio-temporal dynamics of Plasmodium falciparum transmission within a spatial unit on the Colombian Pacific Coast

Spread of artemisinin resistance in Plasmodium falciparum malaria

SV-Pop: population-based structural variant analysis and visualization

Temporal evolution of sulfadoxine-pyrimethamine resistance genotypes and genetic diversity in response to a decade of increased interventions against Plasmodium falciparum in northern Ghana

The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background

THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites

Uptake of intermittent preventive treatment and pregnancy outcomes: health facilities and community surveys in Chókwè district, southern Mozambique

Using CF11 cellulose columns to inexpensively and effectively remove human DNA from Plasmodium falciparum-infected whole blood samples

Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification