Genome-wide study of resistance to severe malaria in eleven populations (version 2)

Project: Consortial Project 1

Released on 15 Aug 2019

This data release contains SNP genotype data and association test results from our analysis of severe malaria in eleven populations. Data for eleven populations (Gambia, Mali, Burkina Faso, Ghana, Nigeria, Cameroon, Tanzania, Malawi, Kenya, Vietnam and Papua New Guinea) are available.

The datasets available include raw Illumina Omni 2.5M genotype data from each population analysed in the above manuscript.  In addition, we provide a set of processed data for a subset of samples that passed our quality control process, including phased and imputed SNP genotypes and a set of association test summary statistics.

15 Aug 2019

Genome-wide phased genotypes for eleven populations

EGA Study ID: EGAS00001001311

8,666 controls; 9,077 cases; 215 parents; 2 other

Method: Illumina Omni 2.5M SNP genotypes phased using SHAPEIT2

Raw genotypes from individual populations are also available as separate datasets (see below).

15 Aug 2019

Gambia

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001738 (2,786 controls; 2,807 cases; 1 parents)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Mali

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001737 (394 controls; 475 cases; 31 parents)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Burkina Faso

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001739 (639 controls; 807 cases)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Ghana

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001734 (342 controls; 422 cases; 18 parents)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Nigeria

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001736 (131 controls; 288 cases)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Cameroon

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001740 (778 controls; 693 cases)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Tanzania

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001743 (494 controls; 485 cases)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Malawi

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001741 (1,498 controls; 1,590 cases)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Kenya

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001742 (1,738 controls; 1,944 cases; 180 parents; 3 other)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Vietnam

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001733 (868 controls; 860 cases)

Method: Illumina Omni 2.5M genotyping

15 Aug 2019

Papua New Guinea

EGA Study ID: EGAS00001001311

EGA Data Set ID: EGAD00010001735 (395 controls; 420 cases)

Method: Illumina Omni 2.5M genotyping