1101 Efficacy of three ACTs in treating falciparum malaria in the Democratic Republic of Congo

Projects:

Locations: Congo (Democratic Republic of the Congo) (CD)

Partner study description

This clinical study aims to assess the efficacy of amodiaquine-artesunate for the treatment of uncomplicated P. falciparum malaria in children in Kinshasa, DRC, five years after its introduction as a first line treatment. It also compares this therapy with the efficacies of dihydroartemisinin-piperaquine and artemether-lumefantrine. Parasite DNA from samples collected from infected patients will be genotyped to perform and association studies with observed clinical phenotypes.

Key People

Caterina A. Fanello
Mahidol Oxford Tropical Medicine Research Unit (MORU), University of Oxford, Thailand
Dr Marie A. Onyamboko
Kinshasa School of Public Health, University of Kinshasa, DRC
Prof Nicholas Day
Mahidol Oxford Tropical Medicine Research Unit (MORU), University of Oxford, Thailand