1101 Efficacy of three ACTs in treating falciparum malaria in the Democratic Republic of Congo

Projects:

Locations: Congo (Democratic Republic of the Congo) (CD)

Partner study description

This clinical study aims to assess the efficacy of amodiaquine-artesunate for the treatment of uncomplicated P. falciparum malaria in children in Kinshasa, DRC, five years after its introduction as a first line treatment. It also compares this therapy with the efficacies of dihydroartemisinin-piperaquine and artemether-lumefantrine. Parasite DNA from samples collected from infected patients will be genotyped to perform and association studies with observed clinical phenotypes.

Key People

Caterina A Fanello
Mahidol Oxford Tropical Medicine Research Unit (MORU), Thailand
Dr Marie A Onyamboko
Kinshasa School of Public Health, University of Kinshasa, DRC
Prof Nicholas Day
Mahidol Oxford Tropical Medicine Research Unit (MORU), Thailand