Using whole-genome sequencing for enhanced monitoring and surveillance of the major African malaria vector Anopheles funestus.
Objectives & Coordination
Anopheles funestus is the second most important human malaria vector species, transmitting Plasmodium parasites in sub-Saharan Africa. This project aims to use whole-genome sequencing to survey genetic diversity, population structure and evolution of An. funestus, and to establish a foundation for ongoing genomic surveillance of An. funestus populations.
Sequencing of mosquitoes from phase 1 of the project is now complete, and has generated whole genome sequence data for more than 800 An. funestus individuals from 15 countries, forming the basis for the first continent-wide An. funestus population genomic analysis. Through 2022, we will be exploring genetic variation and population structure on these phase 1 data. Please reach out to us if you would like to be involved in analysing these data and/or if you would like to participate in future sequencing studies on this important species.
The project is currently open to new partnerships. If you are a vector biologist studying or monitoring mosquitoes in the An. gambiae complex and are interested in partnering with the project, please email the project contact, or see the information about Applying for a Partner Study.