Pan-African Malaria Genetic Epidemiology Network (PAMGEN)




Started 2017

This project aims to create a robust network of African scientists – within and outside Africa– in collaboration with leading researchers around the world, who use the latest genetics and genomics science to contribute towards malaria elimination efforts in Africa. By combining data from across the continent and from across human, parasite, and vector samples, PAMGEN will better understand the deadly evolutionary arms race of malaria.

Objectives & Coordination

The three goals of PAMGEN are to:

  1. Create sustainable, innovative strategies and methods to collect, manage, share and analyse standardised data on human and parasite genetic variation, gene-disease associtions, and gene-environment interactions
  2. Nurture African leadership by identifying and training the next generation of African researchers through advanced degree programmes in genetics and genomics; large-scal datga analysis; and bioethics.
  3. Use human, parasite, and vector population and functional genomics research to drive the development of new tools to support malaria elimination programmes across Africa.

Sampling locations

  • Ghana (GH)
  • The Gambia (GM)
  • Mali (ML)
  • Cameroon (CM)
  • Ethiopia (ET)
  • Madagascar (MG)
  • Tanzania (TZ)

PAMGEN sites

PAMGEN sites: The Gambia, Mali, Ghana, Cameroon, Tanzania, Ethiopia, Madagascar


The PAMGEN project is ambitious and wide-ranging. Its principal investigators span the African continent and have deep experience analysing human, parasite, and vector genomes.

Principal Investigators

The Principal Investigators for PAMGEN represent leading institutions in seven countries across Africa.