At the University of Buea we are performing a family trio study to investigate the genomic basis of resistance against malaria for Consortial Project 3. For this study we needed to identify families where the mother, father and child were all willing to participate. To do this we faced multiple challenges around designing appropriate informed consent processes.
Resistance to the widely used antimalarial drug artemisinin is spreading in Southeast Asia and is likely to be around the corner for Africa. It could reach us very quickly or it could emerge locally.
We don’t want to be surprised by it and we don’t want to be banging our heads against the wall trying to figure out how to deal with it when it comes. We need to be prepared.
Can you tell us a bit about the Plasmodium Diversity Network Africa? What made you want to get involved?
Tell me a bit about what you do.
I’m based in Bangkok at the Mathematical and Economic Modelling Unit (MAEMOD), which is part of the Mahidol Oxford Research Unit (MORU). The main work that we do is economic-epidemioloigcal modelling with a focus on mechanistic approaches, and we also do enhanced data analysis.