Where we work
Through hundreds of partner studies, we work with clinicians, researchers, and malaria control programme specialists in more than 40 malaria-endemic countries.
Below the map is a list of projects and, where applicable, their partner studies.
Click on one or more countries on the map to filter the list of projects by location.
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Genomic Surveillance Hubs in West Africa (NIHR Global Health Research Group)
Started 2022 Malaria is one of the greatest public health challenges facing countries in West Africa. It is responsible for hundreds of thousands of deaths every year and disproportionately affects children in this region of the world. By better understanding the genomic landscape of malaria parasites and vectors in this region, National Malaria Control Programs (NMCPs) can better tailor their responses and save lives. This project will establish the scientific, technical, and operational infrastructure for regional genomic surveillance hubs in West Africa.Sampling locations: Ghana (GH) | The Gambia (GM) | Senegal (SN) | Nigeria (NG) | Burkina Faso (BF) | Guinea (GN) | Sierra Leone (SL) -
Ag1000G
Started 2014 Ag1000G is an international collaboration using whole genome deep sequencing to provide a high-resolution view of genetic variation in natural populations of Anopheles gambiae, the principal vector of Plasmodium falciparum malaria in Africa.Sampling locations: Angola (AO) | Bioko Island, Equatorial Guinea (GQ) | Equatorial Guinea (GQ) | Burkina Faso (BF) | Cameroon (CM) | Gabon (GA) | Ivory Coast (CI) | Kenya (KE) | Mayotte Island (YT) | The Gambia (GM) | Uganda (UG) | Mali (ML) | Central African Republic (CF) | Congo (Democratic Republic of the Congo) (CD) | Tanzania (TZ) | Malawi (MW) | Mozambique (MZ)Partner studies: -
SpotMalaria
Started 2015 SpotMalaria harnesses genomic technologies to monitor the global evolution of malaria parasites, delivering knowledge that will increase the efficiency of malaria elimination and eradication efforts.Sampling locations: Bangladesh (BD) | Cambodia (KH) | Ghana (GH) | Benin (BJ) | Brazil (BR) | Cameroon (CM) | Colombia (CO) | Congo (Democratic Republic of the Congo) (CD) | Ethiopia (ET) | The Gambia (GM) | Guinea (GN) | India (IN) | Indonesia (ID) | Kenya (KE) | Laos (LA) | Malaysia (MY) | Mali (ML) | Myanmar (MM) | Peru (PE) | Senegal (SN) | Sudan (SD) | Tanzania (TZ) | Thailand (TH) | Vietnam (VN)Partner studies: -
P. falciparum Community Project
Started 2010 The P. falciparum Community Project provides researchers with high-quality genotypes linked to a global resource characterising genetic variation in P. falciparum populations.Sampling locations: Bangladesh (BD) | Benin (BJ) | Burkina Faso (BF) | Cambodia (KH) | Cameroon (CM) | Colombia (CO) | Congo (Democratic Republic of the Congo) (CD) | Ethiopia (ET) | Ghana (GH) | Guinea (GN) | Indonesia (ID) | Ivory Coast (CI) | Kenya (KE) | Laos (LA) | Madagascar (MG) | Malawi (MW) | Mali (ML) | Mauritania (MR) | Myanmar (MM) | Nigeria (NG) | Papua New Guinea (PG) | Peru (PE) | Senegal (SN) | Tanzania (TZ) | Thailand (TH) | The Gambia (GM) | Uganda (UG) | Vietnam (VN)Partner studies: -
Vector Observatory - Asia
Started 2019 Vector Observatory - Asia connects research groups that are investigating the population structure and diversity of malaria vectors in Asia. This centres on multiple vectors from the Greater Mekong Subregion in Southeast Asia, where drug-resistant malaria parasites are emerging and spreading. This research is expanding the range of mosquito species that are represented in our whole genome data.Sampling locations: Cambodia (KH) | Thailand (TH) | Bangladesh (BD) -
Consortial Project 1
Started 2005 Consortial Project 1 investigated human genetic factors involved in resistance to severe malaria in order to better understand why, in regions where people are repeatedly exposed to malaria parasites, some people die from the infection while others survive.Sampling locations: Burkina Faso (BF) | Cameroon (CM) | Ghana (GH) | Kenya (KE) | Malawi (MW) | Mali (ML) | Nigeria (NG) | Papua New Guinea (PG) | Tanzania (TZ) | The Gambia (GM) | Vietnam (VN)Partner studies: -
GenRe-Mekong
Started 2016 GenRe-Mekong (Genetic Reconnaissance of Malaria in the Greater Mekong Subregion) is a genetic surveillance project, aiming to provide National Malaria Control Programmes (NMCPs) in the Greater Mekong Subregion and other public health stakeholders with timely and actionable knowledge to support their decision-making in activities relevant to malaria elimination efforts.Sampling locations: Bangladesh (BD) | Cambodia (KH) | Laos (LA) | Myanmar (MM) | Thailand (TH) | Vietnam (VN) | India (IN)Partner studies: -
Consortial Project 2
Started 2005 Consortial Project 2 studied the human genetic factors suspected to influence the antibody response to malaria parasite antigens, with a particular focus on antigens that are being strongly considered for vaccine development.Sampling locations: Burkina Faso (BF) | Kenya (KE) | Mali (ML) | Senegal (SN) | Sri Lanka (LK) | Sudan (SD) | Tanzania (TZ)Partner studies: -
P. vivax Genome Variation
Started 2010 The P. vivax Genome Variation project aims to understand genome diversity of this parasite that, because it can remain dormant in the liver for years, is particularly hard to eliminate using conventional malaria control measures.Sampling locations: Brazil (BR) | Cambodia (KH) | China (CN) | India (IN) | Indonesia (ID) | Laos (LA) | Madagascar (MG) | Malaysia (MY) | Myanmar (MM) | Papua New Guinea (PG) | Sri Lanka (LK) | Thailand (TH) | Vietnam (VN) | Bhutan (BT) | Afghanistan (AF) | Iran (IR)Partner studies: -
Anopheles gambiae genomic surveillance project
Started 2021 Using whole-genome sequencing for enhanced monitoring and surveillance of major malaria vectors in the Anopheles gambiae species complex.Sampling locations: Angola (AO) | Bioko Island, Equatorial Guinea (GQ) | Burkina Faso (BF) | Cameroon (CM) | Central African Republic (CF) | Congo (Democratic Republic of the Congo) (CD) | Equatorial Guinea (GQ) | Gabon (GA) | Ivory Coast (CI) | Kenya (KE) | Malawi (MW) | Mali (ML) | Mayotte Island (YT) | Mozambique (MZ) | Tanzania (TZ) | The Gambia (GM) | Uganda (UG) -
Pf3k
Started 2014 Pf3k is an international collaboration using the latest sequencing technologies to provide a high-resolution view of natural variation in the malaria parasite Plasmodium falciparum.Sampling locations: Bangladesh (BD) | Cambodia (KH) | Congo (Democratic Republic of the Congo) (CD) | Ghana (GH) | Guinea (GN) | Laos (LA) | Malawi (MW) | Mali (ML) | Myanmar (MM) | Nigeria (NG) | Senegal (SN) | Thailand (TH) | The Gambia (GM) | Vietnam (VN)Partner studies: -
Consortial Project 3
Started 2005 Consortial Project 3 used whole genome sequencing to identify genetic diversity in genes known to be associated with resistance to severe malaria, within and across malaria-endemic populations.Sampling locations: Burkina Faso (BF) | Cameroon (CM) | Kenya (KE) | Ghana (GH) | Papua New Guinea (PG) | Tanzania (TZ) | The Gambia (GM) | Vietnam (VN) -
PAMCA-MalariaGEN collaboration
Started 2022 Funded by the Bill and Melinda Gates Foundation and led by The Pan-African Mosquito Control Association (PAMCA), this collaboration aims to establish a new programme of genomic research and data generation on African malaria vectors.Sampling locations: Cameroon (CM) | Congo (Democratic Republic of the Congo) (CD) | Ivory Coast (CI) | Kenya (KE) | Malawi (MW) | South Africa (ZA) | Tanzania (TZ) | The Gambia (GM) | Zambia (ZM) | Zimbabwe (ZW) -
Consortial Project 4
Started 2005 Consortial Project 4 set out to find the specific genes responsible for malaria resistance within genomic regions identified in previous genetic linkage studies.Sampling locations: Senegal (SN) | Thailand (TH)