The Malaria Genomic Epidemiology Network (MalariaGEN) is investigating how genetic variation affects the biology and epidemiology of malaria, and using this knowledge to develop tools to control the disease.
Understanding the evolutionary battle between all three malaria genomes – human, parasite and mosquito – can help inform malaria control interventions.
We're studying the human genome to better understand the genetic factors that help people to resist severe malaria – information that could provide vital clues about the molecular mechanisms of immunity and accelerate the development of an effective vaccine.
We're studying genetic variation in the Anopheles mosquitoes that transmit malaria in order to better understand important evolutionary processes, such as how these mosquitoes adapt to resist infection with malaria parasites and survive insecticides.
We're investigating the biological consequences of genetic variation in the Plasmodium parasites that cause malaria, in order to answer crucial questions about malaria transmission and drug resistance.
