1154 Characterisation of drug resistance in P. falciparum and P. vivax populations from Indonesia and Thailand


Locations: Thailand (TH), Indonesia (ID)

Partner study description

Ric Price, Rintis Noviyanti and Francois Nosten are the principal investigators in a genome-wide study that aims to characterise the molecular profile of drug resistance-conferring variants in Thai and Indonesian parasite populations. The study entails genome-wide scans to identify novel resistance variants as well as characterising known variants in P. falciparum and P. vivax field isolates with ex vivo-determined drug sensitivity profiles for a range of antimalarial drugs. Samples are contributed by consenting patients attending local health centres and hospitals in Indonesia and Thailand. These studies are coordinated by Sarah Auburn and Jutta Marfurt.

Key People

Prof Francois Nosten
Professor in Tropical Medicine, Group Head / PI, Consultant Physician and Fellow
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research building, University of Oxford Old Road campus, Oxford, UK
Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand
Prof Ric N Price
Professor of Tropical Medicine
Centre for Tropical Medicine and Global Health, University of Oxford, UK
Professor of Global Health
Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
Mahidol-Oxford Tropical Medicine Research Unit (MORU), Thailand