Malaria candidate SNP survey in Mali

Last week, Consortial Project 1 partners published a study exploring the influence of sixty-four malaria candidate SNPs, including the sickle-cell polymorphism (HbS), on severe malaria in a case-control study consisting of over 900 individuals from Bamako, Mali. The findings support known protective effects of the blood group O and the HbS AS genotype in relation to life-threatening malaria as well as demonstrating a marginal susceptibility effect for the CD40 ligand (CD40L)+220C allele.

News 13 Sep 2012

Human

Publication

Toure et al. Candidate Polymorphisms and Severe Malaria in a Malian Population.PLoS One. 2012;7(9):e43987. doi: 10.1371/journal.pone.0043987. Epub 2012 Sep 5.

Latest news and events

News 27 Apr 2026 Genomic insights into insecticide resistance in South American malaria vectors Foundational research on the primary malaria vector for South America, Anopheles darlingi, in a testament to open data sharing, contributes to MalariaGEN’s Vector Observatory.

26 Mar 2026 March 2026 MalariaGEN Community Newsletter In this issue: Prof Djimde new appointment | MalariaGEN Training Blog | Global Fund opportunities | WHO news | Harvard on-line training

Article 26 Feb 2026 Building Genomics Capacity for Malaria Surveillance in Africa: Training Resources Identifying training opportunities for genomic epidemiology of malaria.