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Malaria candidate SNP survey in Mali

Last week, Consortial Project 1 partners published a study exploring the influence of sixty-four malaria candidate SNPs, including the sickle-cell polymorphism (HbS), on severe malaria in a case-control study consisting of over 900 individuals from Bamako, Mali. The findings support known protective effects of the blood group O and the HbS AS genotype in relation to life-threatening malaria as well as demonstrating a marginal susceptibility effect for the CD40 ligand (CD40L)+220C allele.

News 13 Sep 2012
Human

Publication

Toure et al. Candidate Polymorphisms and Severe Malaria in a Malian Population.PLoS One. 2012;7(9):e43987. doi: 10.1371/journal.pone.0043987. Epub 2012 Sep 5.

Latest news and events

News 8 Sep 2025 MalariaGEN hosts two Google Summer of Code projects with promising malaria genomics talent This summer, Mohamed Laarej and Deepak Silaych were supported through the Google Summer of Code 2025 initiative to work with MalariaGEN on projects to better understand mosquito populations in Africa. Both are new…
Newsletter Banner Newsletter 29 Jul 2025 July 2025 MalariaGEN Community Newsletter In this issue: Pf8 is released | MalariaGEN 20th anniversary | Timor Leste Malaria-free Malaria surge in Southern Africa | Vector Selection Atlas
Large white text reads "Pf8," overlaid on top of an image of a world map at night showing with lights across the world. News 1 Jul 2025 Pf8 released: A major update for the world’s largest malaria parasite genomic data resource Containing 33,325 whole genomes of Plasmodium falciparum parasites from blood samples collected in 122 different locations across 56 years, Pf8 provides unprecedented opportunities to understand and combat malaria.

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