Whole-genome sequencing of P. vivax field isolates

A recent study reports the whole genome sequencing of five P. vivax isolates taken directly from blood samples of infected patients in Cambodia and Madagascar, as well as the Belem strain that is adapted to survive in monkeys. Each patient was found to be infected with multiple vivax strains. Researchers identified a catalogue of 80,000 SNPs, which can be used for large-scale genotyping and association mapping studies.

News 16 Sep 2012

Publication

Chan et al. Whole Genome Sequencing of Field Isolates Provides Robust Characterization of Genetic Diversity in Plasmodium vivax. PLoS Negl Trop Dis. 2012;6(9):e1811. doi: 10.1371/journal.pntd.0001811. Epub 2012 Sep 6.

Coverage

GENNewsHighlights: Five Malaria Genomes Sequenced
GenomeWeb Daily News: Team Determines Malaria Parasite Genomes, Diversity with DNA from Patient Samples (requires free login)

Latest news and events

29 May 2025 May 2025 MalariaGEN Community Newsletter In this issue: Construction in Cameroon | Anopheles surveillance in Africa | World Health Assembly | Parasite surveillance in the GMS | Drugs for mosquitoes

29 Apr 2025 April 2025 MalariaGEN Community Newsletter In this issue: World Malaria Day 2025, Deciphering Drug Resistance Over 30 Years, May Journal Club, Pwani Molecular Form, and SciDev Blog with Prof Abdoulaye Djimde.

31 Mar 2025 March 2025 MalariaGEN Community Newsletter In this issue: Vector Training 2025, April Journal Club, PlasmoGenEpi Course, Parasite Time Capsule, and the AnoKin Project.