Whole-genome sequencing of P. vivax field isolates

A recent study reports the whole genome sequencing of five P. vivax isolates taken directly from blood samples of infected patients in Cambodia and Madagascar, as well as the Belem strain that is adapted to survive in monkeys. Each patient was found to be infected with multiple vivax strains. Researchers identified a catalogue of 80,000 SNPs, which can be used for large-scale genotyping and association mapping studies.

News 16 Sep 2012

Publication

Chan et al. Whole Genome Sequencing of Field Isolates Provides Robust Characterization of Genetic Diversity in Plasmodium vivax. PLoS Negl Trop Dis. 2012;6(9):e1811. doi: 10.1371/journal.pntd.0001811. Epub 2012 Sep 6.

Coverage

GENNewsHighlights: Five Malaria Genomes Sequenced
GenomeWeb Daily News: Team Determines Malaria Parasite Genomes, Diversity with DNA from Patient Samples (requires free login)

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