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Catalogue of Genetic Variation in P. falciparum - v1.0

Released on 22 May 2012.

Parasite

An important output of the P. falciparum Community Project is the Catalogue of Genetic Variation in P. falciparum, which includes:

  • Single nucleotide polymorphisms (SNPs) identified via deep sequencing
  • Allele frequencies in different geographical populations
  • Measures of genome accessibility – such as %GC, mapping quality and coverage – to visualise potential difficulties in identifying SNPs and accurately genotyping samples

The data in the Catalogue of Genetic Variation in P. falciparum are periodically updated and made available open access.

Data sets

Catalogue of Genetic Variation in P. falciparum - v1.0

Download our intial Catalogue of Genetic Variation in P. falciparum (v1.0) which contains 86,000 SNPs and allele frequency data based on an analysis of 227 P. falciparum samples collected in six different loactions in Africa, Asia, and Oceania.

These data can be downloaded from the Wellcome Trust Sanger Institute public ftp site.

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These data are described in Manske, Miotto et al, 2012.

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Citations

Manske M., Miotto O. et al. Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. Nature. 2012 July 19; 487: 375-379. PMID 22722859