1020 Measuring in vitro drug sensitivity in Vietnam

Partner study description

Samples were collected in the southern province of Binh Phuoc, Vietnam, as part of a set of clinical studies initiated by Professor Tran Tinh Hien and Christiane Dolecek in 2009 to measure in vivo and in vitro drug sensitivity in this region. In collaboration with Maciej Boni, Professor Hien's research team also worked towards characterising signatures of sulfadoxine/pyrimethamine and chloroquine resistance, and pfMDR copy number in these samples using the Illumina sequence and genotype data.

Where samples were found to contain P. vivax data, for example due to mixed infection, this data was contributed to the P. vivax Genome Variation project.

Key People

Dr Christiane Dolecek
Nuffield Department of Medicine, University of Oxford, UK
Prof Maciej Boni
Head of Mathematical Modelling Group
Oxford University Clinical Research Unit (OUCRU), Vietnam
Associate Professor
Nuffield Department of Medicine, University of Oxford, UK