This study aims to use genome-wide sequencing to establish the structure of Plasmodium populations in an endemic area of low malaria transmission with occasional outbreaks, in the Pacific region of Colombia, and analyse the emergence, dissemination, and frequency changes of antimalarial drug resistance genotypes, the connectivity between parasite populations, and the way epidemiologic and demographic variables affect some of the parasite's genetic properties. Patterns of malaria transmission and parasite molecular information allow to characterize spatial malaria transmission units to inform malaria control programmes.
1169 Using genomic sequencing to diminish the malaria burden in the Pacific coast of Colombia
Dr Julian C Rayner
Senior Group Leader, Malaria Programme
Wellcome Sanger Institute, UK
Director, Courses, Conferences and Public Engagement Programme
Wellcome Genome Campus, UK