Partner study description
As part of his PhD research Harold Ocholla worked with colleagues at the Liverpool School of Tropical Medicine and in Malawi to collect uncultured paediatric Plasmodium falciparum isolates from malaria patients in a region of high malaria transmission in the Chikwawa and Zomba districts of Malawi over multiple malaria seasons. The goal of his work is to map genome variation and genetic signatures of evolutionary selection in these parasite populations in space and time, to identify associations between genetic variants and important clinical malaria phenotypes.
Genomic epidemiology of artemisinin resistant malaria
MalariaGEN P. falciparum Community ProjecteLife, 2016; 5 e08714
Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates
Ocholla et al.Journal of Infectious Diseases, 2014; 210(12) 1991-2000