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1100 Drug resistance and Plasmodium falciparum diversity in forest zone of Côte d’Ivoire

Location: Ivory Coast (CI).


Partner study description

William Yavo is investigating Plasmodium falciparum parasite population structures according to epidemiological facies and their impact on artemisinin combination therapy (ACT) treatment failure. Samples of the parasites were collected in the urban and suburban areas of Abidjan (economic capital of Côte d’Ivoire), the forest and coastal zone of San Pedro as well as from Abengourou (transition forest zone in the East of the country), during clinical trials comparing Artesunate-Amodiaquine vs Artemether-Lumefantrine according to WHO protocol. This study is contributing to the Plasmodium Diversity Network Africa (PDNA), an African-led network investigating the genetic diversity and drug resistance of Plasmodium parasites across Africa.