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1101 Efficacy of three ACTs in treating falciparum malaria in the Democratic Republic of Congo

Location: Congo (Democratic Republic of the Congo) (CD).


Partner study description

This clinical study aims to assess the efficacy of amodiaquine-artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in children in Kinshasa, DRC, five years after its introduction as a first line treatment. It also compares this therapy with the efficacies of dihydroartemisinin-piperaquine and artemether-lumefantrine. Parasite DNA from samples collected from infected patients will be genotyped to perform and association studies with observed clinical phenotypes.