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1154 Characterisation of drug resistance in P. falciparum and P. vivax populations from Indonesia and Thailand

Locations: Indonesia (ID), Thailand (TH).


Partner study description

Ric Price, Rintis Noviyanti and Francois Nosten are the principal investigators in a genome-wide study that aims to characterise the molecular profile of drug resistance-conferring variants in Thai and Indonesian parasite populations. The study entails genome-wide scans to identify novel resistance variants as well as characterising known variants in P. falciparum and P. vivax field isolates with ex vivo-determined drug sensitivity profiles for a range of antimalarial drugs. Samples are contributed by consenting patients attending local health centres and hospitals in Indonesia and Thailand. These studies are coordinated by Sarah Auburn and Jutta Marfurt.