Introduction

Using whole-genome sequencing for enhanced monitoring and surveillance of the malaria vector Anopheles darlingi.

Objectives & Coordination

Anopheles darlingi is the primary human malaria vector species in South America and plays a key role in transmitting Plasmodium parasites in the Amazon Basin. This project was established to investigate if key characteristics observed in An. gambiae and An. funestus malaria vectors, such as the complex taxa, high genetic diversity and distinct evolutionary histories are also  observed in An. darlingi. This resource  features whole-genome sequence data which can be used to survey genetic diversity, population structure and evolution of An. darlingi, and to establish a foundation for ongoing genomic surveillance of An. darlingi populations.

Status

Researchers from The Broad Institute of MIT and Harvard have generated whole genome sequence data for more than 1000 An. darlingi individuals from six countries, forming the basis for the first large open data resource on the main malaria vector in the Amazon basin or any neotropical mosquito. 

Locations

Samples were collected from 16 sites across Colombia, Venezuela, Peru, Brazil, French Guiana and Guyana between the years 2011 and 2023

Sampling locations

Brazil, Colombia, Guyana, Peru, Venezuela.

Data

Analysis-ready whole genome sequence data of over 1000 specimens of An. darlingi, sampled and sequenced by the project partners, is now available on the Malaria Vector Genome Observatory. 

To find out more about currently available data please visit the Vector Data User Guide.

Current

Mosquito 5 Dec 2025 Adar1.0 SNP data release

This data release includes whole genome sequences from over 1000 An. darlingi mosquitoes collected from 16 different sites across Colombia, Venezuela, Peru, Brazil, French Guiana and Guyana.

Partner studies

Partner study Anopheles darlingi vector surveillance in Brazil (1357-VO-BR-SALLUM) 

Anopheles darlingi is the primary human malaria vector species in South America and plays a key role in transmitting Plasmodium parasites in the Amazon Basin.  These specimens were collected by researchers in Brazil…

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Partner study Anopheles darlingi vector surveillance in Colombia (1362-VO-CO-QUINONES)

Anopheles darlingi is the primary human malaria vector species in South America and plays a key role in transmitting Plasmodium parasites in the Amazon Basin.  These specimens were collected by researchers in Colombia…

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Partner study Anopheles darlingi vector surveillance in French Guiana (1358-VO-GF-GENDRIN) 

Anopheles darlingi is the primary human malaria vector species in South America and plays a key role in transmitting Plasmodium parasites in the Amazon Basin.  These specimens were collected by researchers in French…

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Partner study Anopheles darlingi vector surveillance in Guyana (1359-VO-GY-NILES-ROBIN) 

Anopheles darlingi is the primary human malaria vector species in South America and plays a key role in transmitting Plasmodium parasites in the Amazon Basin.  These specimens were collected by researchers in Guyana…

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Partner study Anopheles darlingi vector surveillance in Venezuela (1361-VO-VE-GRILLET)

Anopheles darlingi is the primary human malaria vector species in South America and plays a key role in transmitting Plasmodium parasites in the Amazon Basin.  These specimens were collected by researchers in Venezuela …

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Partner study Anopheles darlingi vector surveillance in Peru (1360-VO-PE-GAMBOA)

Anopheles darlingi is the primary human malaria vector species in South America and plays a key role in transmitting Plasmodium parasites in the Amazon Basin.  These specimens were collected by researchers in Peru…

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