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Pan-African Malaria Genetic Epidemiology Network (PAMGEN)

Started 2017

Human Mosquito Parasite
 

Introduction

This project aims to create a robust network of African scientists – within and outside Africa– in collaboration with leading researchers around the world, who use the latest genetics and genomics science to contribute towards malaria elimination efforts in Africa. By combining data from across the continent and from across human, parasite, and vector samples, PAMGEN will better understand the deadly evolutionary arms race of malaria.

Objectives & Coordination

The three goals of PAMGEN are to:

  1. Create sustainable, innovative strategies and methods to collect, manage, share and analyse standardised data on human and parasite genetic variation, gene-disease associtions, and gene-environment interactions
  2. Nurture African leadership by identifying and training the next generation of African researchers through advanced degree programmes in genetics and genomics; large-scal datga analysis; and bioethics.
  3. Use human, parasite, and vector population and functional genomics research to drive the development of new tools to support malaria elimination programmes across Africa.

Sampling locations

Cameroon, Ethiopia, The Gambia, Ghana, Madagascar, Mali, Tanzania.

PAMGEN sites

PAMGEN sites: The Gambia, Mali, Ghana, Cameroon, Tanzania, Ethiopia, Madagascar

Partner studies

The project is divided into four separate studies, according to P. falciparum parasite data, P. vivax parasite data, vector data and human data.

31 May 2023 1268 Pan-African Malaria Genetic Epidemiology Network (PAMGEN) Plasmodium falciparum samples

Partner study description The Plasmodium falciparum samples due to be collected from seven countries (The Gambia, Ghana, Mali, Cameroon, Ethiopia, Tanzania and Madagascar) will contribute to the Pan-African Malaria Genetic Epidemiology Network (PAMGEN)…

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31 May 2023 1269 Pan-African Malaria Genetic Epidemiology Network (PAMGEN) Plasmodium vivax samples

Partner study description The Plasmodium vivax samples due to be collected from Ethiopia and Madagascar will contribute to the Pan-African Malaria Genetic Epidemiology Network (PAMGEN) project. The aim of PAMGEN is to create…

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7 Sep 2023 Pan-African Malaria Genetic Epidemiology Network (PAMGEN) Anopheles gambiae samples (1270-VO-MULTI-PAMGEN)

The Anopheles gambiae samples due to be collected from seven countries (The Gambia, Ghana, Mali, Cameroon, Ethiopia, Tanzania and Madagascar) will contribute to the Pan-African Malaria Genetic Epidemiology Network (PAMGEN) project. The aim…

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Project contact

People

The PAMGEN project is ambitious and wide-ranging. Its principal investigators span the African continent and have deep experience analysing human, parasite, and vector genomes.

Principal Investigators

The Principal Investigators for PAMGEN represent leading institutions in seven countries across Africa.

Project news

Blog

Understanding the human genes locking out malaria parasites

“If I don’t like you coming to my house, I change the locks.” We talk to Dr Dominic S. Y. Amuzu about his research into genetic variations keeping severe malaria at bay in West Africa.

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