Publications
Featured publications
8 Apr 2022
An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
Wellcome Open Research 2022 7 136 DOI: https://doi.org/10.12688/wellcomeopenres.17795.124 Feb 2021
An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples
Wellcome Open Research 2021 6 42 DOI: 10.12688/wellcomeopenres.16168.128 Sep 2020
Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii
Genome Research 2020 30 1533-1546 DOI: 10.1101/gr.262790.12016 Dec 2019
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
Nature Communications 2019 10 5732 DOI: 10.1038/s41467-019-13480-z1 Feb 2018
Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study
The Lancet Infectious Diseases 2018 18 337-345 DOI: 10.1016/S1473-3099(18)30068-929 Nov 2017
Genetic diversity of the African malaria vector Anopheles gambiae
Nature 2017 DOI: 10.1038/nature2499527 Jun 2016
Genomic analysis of local variation and recent evolution in Plasmodium vivax
Nature Genetics 2016 48 959-964 DOI: 10.1038/ng.359911 Dec 2008
A global network for investigating the genomic epidemiology of malaria
Nature 2008 456(7223) 732-7 DOI: 10.1038/nature07632Latest publications
19 Apr 2022
Protective Immunity against Severe Malaria in Children Is Associated with a Limited Repertoire of Antibodies to Conserved PfEMP1 Variants
Cell Host & Microbe 2019 26(5) 579-590.e5 DOI: https://doi.org/10.1016/j.chom.2019.10.01219 Apr 2022
Global diversity and balancing selection of 23 leading Plasmodium falciparum candidate vaccine antigens
PLoS Computational Biology 2022 18(2) e1009801 DOI: https://doi.org/10.1371/journal.pcbi.100980119 Apr 2022
Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea
PLoS Pathogens 2020 16(12) e1009133 DOI: https://doi.org/10.1371/journal.ppat.10091338 Apr 2022
Plasmodium malariae and Plasmodium ovale infections and their association with common red blood cell polymorphisms in a highly endemic area of Uganda
Transactions of The Royal Society of Tropical Medicine and Hygiene 2019 113(7) 370-378 DOI: https://doi.org/10.1093/trstmh/trz0158 Apr 2022
Influence of infection on malaria-specific antibody dynamics in a cohort exposed to intense malaria transmission in northern Uganda
Parasite Immunology 2013 35(5-6) 164-73 DOI: https://doi.org/10.1111/pim.120314 Apr 2022
Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response
Communications Biology 2022 5 274 DOI: https://doi.org/10.1038/s42003-022-03215-04 Apr 2022
Molecular epidemiology of resistance to antimalarial drugs in the Greater Mekong subregion: an observational study
The Lancet Infectious Diseases 2020 20(12) 1470-1480 DOI: https://doi.org/10.1016/S1473-3099(20)30228-09 Dec 2021
The protective effect of sickle cell haemoglobin against severe malaria depends on parasite genotype
Malaria protection due to sickle haemoglobin depends on parasite genotype 2021 DOI: https://doi.org/10.1038/s41586-021-04288-310 Aug 2021
Genetic surveillance in the Greater Mekong Subregion and South Asia to support malaria control and elimination: about the data
eLife 2021 10:e62997 DOI: 10.7554/eLife.6299710 Aug 2021
Genetic surveillance in the Greater Mekong Subregion and South Asia to support malaria control and elimination: about the data
eLife 2021 10:e62997 DOI: 10.7554/eLife.629977 Jun 2021
Arterolane–piperaquine–mefloquine versus arterolane–piperaquine and artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a single-centre, open-label, randomised, non-inferiority trial
The Lancet Infectious Diseases 2021 20 30929-4 DOI: 10.1016/S1473-3099(20)30929-425 May 2021
A. Genetic variation at the Cyp6m2 putative insecticide resistance locus in Anopheles gambiae and Anopheles coluzzii.
Malaria Journal 2021 20 234 DOI: 10.1186/s12936-021-03757-431 Mar 2021
Genomic analysis reveals independent evolution of Plasmodium falciparum populations in Ethiopia
Malaria Journal 2021 20 129 DOI: https://doi.org/10.1186/s12936-021-03660-y31 Mar 2021
Genomic analysis reveals independent evolution of Plasmodium falciparum populations in Ethiopia
Malaria Journal 2021 20 129 DOI: https://doi.org/10.1186/s12936-021-03660-y9 Mar 2021
Discovery of Ongoing Selective Sweeps within Anopheles Mosquito Populations Using Deep Learning.
Mol Biol Evol 2021 38 1168-1183 DOI: 10.1093/molbev/msaa25915 Feb 2021
Novel genotyping approaches to easily detect genomic admixture between the major Afrotropical malaria vector species, Anopheles coluzzii and An. gambiae
Mol Ecol Resour. 2021 DOI: 10.1111/1755-0998.1335921 Jan 2021
Resistance to pirimiphos-methyl in West African Anopheles is spreading via duplication and introgression of the Ace1 locus.
PLoS Genetics 2021 17 DOI: 10.1371/journal.pgen.10092531 Oct 2020
Evolution of the Insecticide Target Rdl in African Anopheles Is Driven by Interspecific and Interkaryotypic Introgression
Mol Biol Evol 2020 1 37 DOI: 10.1093/molbev/msaa12821 Jan 2019
Genomic analysis of Plasmodium vivax in southern Ethiopia reveals selective pressures in multiple parasite mechanisms.
The Journal of Infectious Diseases 2019 220 1738-1749 DOI: 10.1093/infdis/jiz01617 Dec 2018
Host genetic polymorphisms and serological response against malaria in a selected population in Sri Lanka
Malaria Journal 2018 17 473 DOI: 10.1186/s12936-018-2622-94 Dec 2018
The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background
Nature Communications 2018 9 5158 DOI: 10.1038/s41467-018-07588-x29 Nov 2018
A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways
PLoS Pathogens 2018 4(11) DOI: https://doi.org/10.1371/journal.ppat.100743625 Oct 2018
Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development
Scientific Reports 2018 8 15763 DOI: 10.1038/s41598-018-34078-323 Jul 2018
Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLbeta Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea
Infection and Immunity 2018 86 e00485-17 DOI: 10.1128/IAI.00485-1719 Jul 2018
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
The Lancet Haematology 2018 5 DOI: 10.1016/S2352-3026(18)30107-826 Jun 2018
Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia
Scientific Reports 2018 8 9687 DOI: 10.1038/s41598-018-28017-517 May 2018
Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics
Nature Communications 2018 9 2585 DOI: 10.1038/s41467-018-04965-4- 1 of 4
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