Publications

Latest publications

23 May 2013

Imputation-based meta-analysis of severe malaria in three African populations

Band G, Le QS, Jostins L, Pirinen M, Kivinen K, Jallow M, Sisay-Joof F, Bojang K, Pinder M, Sirugo G, Conway DJ, Nyirongo V, Kachala D, Molyneux M, Taylor T, Ndila C, Peshu N, Marsh K, Williams TN, Alcock D, Andrews R, Edkins S, Gray E, Hubbart C, Jeffreys A, Rowlands K, Schuldt K, Clark TG, Small KS, Teo YY, Kwiatkowski DP, Rockett KA, Barrett JC, Spencer CC; Malaria Genomic Epidemiology Network
PloS Genetics 2013 9(5) e1003509 DOI: 10.1371/journal.pgen.1003509
28 Apr 2013

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

Miotto O, Almagro-Garcia J, Manske M, Macinnis B, Campino S, Rockett KA, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Duong S, Nguon C, Chuor CM, Saunders D, Se Y, Lon C, Fukuda MM, Amenga-Etego L, Hodgson AV, Asoala V, Imwong M, Takala-Harrison S, Nosten F, Su XZ, Ringwald P, Ariey F, Dolecek C, Hien TT, Boni MF, Thai CQ, Amambua-Ngwa A, Conway DJ, Djimdé AA, Doumbo OK, Zongo I, Ouedraogo JB, Alcock D, Drury E, Auburn S, Koch O, Sanders M, Hubbart C, Maslen G, Ruano-Rubio V, Jyothi D, Miles A, O'Brien J, Gamble C, Oyola SO, Rayner JC, Newbold CI, Berriman M, Spencer CC, McVean G, Day NP, White NJ, Bethell D, Dondorp AM, Plowe CV, Fairhurst RM, Kwiatkowski DP
Nature Genetics 2013 45(6) 648-55 DOI: 10.1038/ng.2624
1 Nov 2012

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites

Amambua-Ngwa A, Tetteh KK, Manske M, Gomez-Escobar N, Stewart LB, Deerhake ME, Cheeseman IH, Newbold CI, Holder AA, Knuepfer E, Janha O, Jallow M, Campino S, Macinnis B, Kwiatkowski DP, Conway DJ
PLoS Genetics 2012 8(11) e1002992 DOI: 10.1371/journal.pgen.1002992
29 Oct 2012

Candidate human genetic polymorphisms and severe malaria in a Tanzanian population

Manjurano A, Clark TG, Nadjm B, Mtove G, Wangai H, Sepulveda N, Campino SG, Maxwell C, Olomi R, Rockett KR, Jeffreys A, MalariaGen Consortium, Riley EM, Reyburn H, Drakeley C
PLoS One 2012 7(10) e47463 DOI: 10.1371/journal.pone.0047463
5 Sep 2012

Candidate polymorphisms and severe malaria in a Malian population

Toure O, Konate S, Sissoko S, Niangaly A, Barry A, Sall AH, Diarra E, Poudiougou B, Sepulveda N, Campino S, Rockett KA, Clark TG, Thera MA, Doumbo O; in collaboration with the MalariaGEN Consortium
PLoS One 2012 7(9) e43987 DOI: 10.1371/journal.pone.0043987
1 Sep 2012

Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese

Dunstan SJ, Rockett KA, Quyen NT, Teo YY, Thai CQ, Hang NT, Jeffreys A, Clark TG, Small KS, Simmons CP, Day N, O'Riordan SE, Kwiatkowski DP, Farrar J, Phu NH, Hien TT; MalariaGEN Consortium
Genes Immunology 2012 13(6) 503-8 DOI: 10.1038/gene.2012.25
20 Aug 2012

Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka

Dewasurendra RL, Suriyaphol P, Fernando SD, Carter R, Rockett K, Corran P, Kwiatkowski D, Karunaweera ND; MalariaGEN Consortium
Malaria Journal 2012 11 281 DOI: doi:10.1186/1475-2875-11-281
19 Jul 2012

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

Manske M, Miotto O, Campino S, Auburn S, Almagro-Garcia J, Maslen G, O'Brien J, Djimde A, Doumbo O, Zongo I, Ouedraogo JB, Michon P, Mueller I, Siba P, Nzila A, Borrmann S, Kiara SM, Marsh K, Jiang H, Su XZ, Amaratunga C, Fairhurst R, Socheat D, Nosten F, Imwong M, White NJ, Sanders M, Anastasi E, Alcock D, Drury E, Oyola S, Quail MA, Turner DJ, Ruano-Rubio V, Jyothi D, Amenga-Etego L, Hubbart C, Jeffreys A, Rowlands K, Sutherland C, Roper C, Mangano V, Modiano D, Tan JC, Ferdig MT, Amambua-Ngwa A, Conway DJ, Takala-Harrison S, Plowe CV, Rayner JC, Rockett KA, Clark TG, Newbold CI, Berriman M, MacInnis B, Kwiatkowski DP
Nature 2012 487(7407) 375-9 DOI: 10.1038/nature11174
2 Jul 2012

Seeking consent to genetic and genomic research in a rural Ghanaian setting: a qualitative study of the MalariaGEN experience

Tindana P, Bull S, Amenga-Etego L, de Vries J, Aborigo R, Koram K, Kwiatkowski D, Parker M
BMC Medical Ethics 2012 13 15 DOI: 10.1186/1472-6939-13-15
24 Jun 2012

Severe and uncomplicated falciparum malaria in children from three regions and three ethnic groups in Cameroon: prospective study

Achidi EA, Apinjoh TO, Anchang-Kimbi JK, Mugri RN, Ngwai AN, Yafi CN
Malaria Journal 2012 11 215 DOI: 10.1186/1475-2875-11-215
16 Jun 2012

Investigating the potential for ethnic group harm in collaborative genomics research in Africa: is ethnic stigmatisation likely?

de Vries J, Jallow M, Williams TN, Kwiatkowski D, Parker M, Fitzpatrick R
Social Science & Medicine 2012 75(8) 1400-7 DOI: 10.1016/j.socscimed.2012.05.020
7 Jun 2012

Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese

Dunstan SJ, Rockett KA, Quyen NT, Teo YY, Thai CQ, Hang NT, Jeffreys A, Clark TG, Small KS, Simmons CP, Day N, O'Riordan SE, Kwiatkowski DP, Farrar J, Phu NH, Hien TT; in collaboration with the MalariaGEN Consortium
Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese 2012 13(6) 503-8 DOI: 10.1038/gene.2012.25
29 Feb 2012

Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data

Auburn S, Campino S, Miotto O, Djimde AA, Zongo I, Manske M, Maslen G, Mangano V, Alcock D, MacInnis B, Rockett KA, Clark TG, Doumbo OK, Ouédraogo JB, Kwiatkowski DP
PLoS One 2012 7(2) e32891 DOI: 10.1371/journal.pone.0032891
18 Nov 2011

Ethical issues in human genomics research in developing countries

de Vries J, Bull SJ, Doumbo O, Ibrahim M, Mercereau-Puijalon O, Kwiatkowski D, Parker M
BMC Medical Ethics 2011 12 5 DOI: 10.1186/1472-6939-12-5
11 Aug 2011

Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients

Robinson T, Campino SG, Auburn S, Assefa SA, Polley SD, Manske M, MacInnis B, Rockett KA, Maslen GL, Sanders M, Quail MA, Chiodini PL, Kwiatkowski DP, Clark TG, Sutherland CJ
PLoS One 2011 6(8) e23204 DOI: 10.1371/journal.pone.0023204
18 Jul 2011

An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing

Auburn S, Campino S, Clark TG, Djimde AA, Zongo I, Pinches R, Manske M, Mangano V, Alcock D, Anastasi E, Maslen G, Macinnis B, Rockett K, Modiano D, Newbold CI, Doumbo OK, Ouédraogo JB, Kwiatkowski DP
PLoS One 2011 6(7) e22213 DOI: 10.1371/journal.pone.0022213
6 Jun 2011

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay

Campino S, Auburn S, Kivinen K, Zongo I, Ouedraogo JB, Mangano V, Djimde A, Doumbo OK, Kiara SM, Nzila A, Borrmann S, Marsh K, Michon P, Mueller I, Siba P, Jiang H, Su XZ, Amaratunga C, Socheat D, Fairhurst RM, Imwong M, Anderson T, Nosten F, White NJ, Gwilliam R, Deloukas P, MacInnis B, Newbold CI, Rockett K, Clark TG, Kwiatkowski DP
PLoS One 2011 6(6) e20251 DOI: 10.1371/journal.pone.0020251
1 Feb 2010

Methodological challenges of genome-wide association analysis in Africa

Teo YY, Small KS, Kwiatkowski DP
Nature Reviews Genetics 2010 11(2) 149-60 DOI: 10.1038/nrg2731
24 Nov 2009

Ethical data-release in genome-wide association studies in developing countries

Parker M, Bull SJ, de Vries J, Agbenyega T, Doumbo OK, Kwiatkowski DP
PLoS Medicine 2009 6(11) e1000143 DOI: 10.1371/journal.pmed.1000143
24 May 2009

Genome-wide and fine-resolution association analysis of malaria in West Africa

Jallow M, Teo YY, Small KS, Rockett KA, Deloukas P, Clark TG, Kivinen K, Bojang KA, Conway DJ, Pinder M, Sirugo G, Sisay-Joof F, Usen S, Auburn S, Bumpstead SJ, Campino S, Coffey A, Dunham A, Fry AE, Green A, Gwilliam R, Hunt SE, Inouye M, Jeffreys AE, Mendy A, Palotie A, Potter S, Ragoussis J, Rogers J, Rowlands K, Somaskantharajah E, Whittaker P, Widden C, Donnelly P, Howie B, Marchini J, Morris A, SanJoaquin M, Achidi EA, Agbenyega T, Allen A, Amodu O, Corran P, Djimde A, Dolo A, Doumbo OK, Drakeley C, Dunstan S, Evans J, Farrar J, Fernando D, Hien TT, Horstmann RD, Ibrahim M, Karunaweera N, Kokwaro G, Koram KA, Lemnge M, Makani J, Marsh K, Michon P, Modiano D, Molyneux ME, Mueller I, Parker M, Peshu N, Plowe CV, Puijalon O, Reeder J, Reyburn H, Riley EM, Sakuntabhai A, Singhasivanon P, Sirima S, Tall A, Taylor TE, Thera M, Troye-Blomberg M, Williams TN, Wilson M, Kwiatkowski DP; Wellcome Trust Case Control Consortium; Malaria Genomic Epidemiology Network
Nature Genetics 2009 41(6) 657-65 DOI: 10.1038/ng.388