Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

28 Apr 2013

Miotto O, Almagro-Garcia J, Manske M, Macinnis B, Campino S, Rockett KA, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Duong S, Nguon C, Chuor CM, Saunders D, Se Y, Lon C, Fukuda MM, Amenga-Etego L, Hodgson AV, Asoala V, Imwong M, Takala-Harrison S, Nosten F, Su XZ, Ringwald P, Ariey F, Dolecek C, Hien TT, Boni MF, Thai CQ, Amambua-Ngwa A, Conway DJ, Djimdé AA, Doumbo OK, Zongo I, Ouedraogo JB, Alcock D, Drury E, Auburn S, Koch O, Sanders M, Hubbart C, Maslen G, Ruano-Rubio V, Jyothi D, Miles A, O'Brien J, Gamble C, Oyola SO, Rayner JC, Newbold CI, Berriman M, Spencer CC, McVean G, Day NP, White NJ, Bethell D, Dondorp AM, Plowe CV, Fairhurst RM, Kwiatkowski DP

Nature Genetics 2013 45(6) 648-55 DOI: 10.1038/ng.2624

Data resources

Explore the latest P. falciparum Community Project data release in our interactive web application
Catalogue of genetic variations (SNPs) and allele frequencies v1.0 - Download the intial catalogue of 86,000 SNPs and allele frequency data described in Manske, Miotto, et al (2012).
Sample information - Download information about the samples and sequence data included in published population-level analyses

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About the collaboration

The sequence data used in this analysis were generated by the Wellcome Trust Sanger Institute and contributed to the MalariaGEN P. falciparum Community Project by several independent research groups, and forms part of an ongoing project to characterise all common forms of genetic variation in the P. falciparum population. This work is expected to have many scientific and translational applications, and aims to foster the use of parasite sequencing and genotyping to guide malaria control and elimination strategies.