Culture adaptation of malaria parasites selects for convergent loss-of-function mutants

24 Jan 2017
Claessens A, Affara M, Assefa SA, Kwiatkowski DP, Conway DJ
Scientific Reports 2017 7 41303 DOI: 10.1038/srep41303

Data resources

Genotypes cultured Isolates

Genotype calls on 944,270 SNPs on the sequences of different time points during culture adaptation of six Gambian isolates. These genotypes were generated using version 4.0 of the MalariaGEN P. falciparum Community Project analysis pipeline.

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Genotypes Pf3k project

Genotype calls on 944,270 SNPs on the sequences of 2,512 samples from Pf3k pilot data release 3 generated as part of the Pf3k project.

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About the collaboration

This study used data generated by the MalariaGEN P. falciparum Community Project, an international collaboration that is aims to understand genome diversity of this parasite.