1208 Genetic epidemiology of Plasmodium falciparum malaria and associated antimalarial drug resistance in Lao PDR

Genetic surveillance project conducted by the National Malaria Control Programme in partnership with GenRe-Mekong in endemic region of the Lao PDR. This is part of a large project of genetic surveillance of malaria in the Greater Mekong Subregion, funded by the Bill and Melinda Gates Foundation. Dried blood spot (DBS) samples are to be collected along with short surveys on patient demographics and population movement from every confirmed case of Plasmodium falciparum and/or Plasmodium vivax malaria presenting at public health facilities. The aim is to determine the prevalence and geographic distribution of antimalarial drug resistance-linked genetic mutations, as well as the genetic structure of the parasite population, likely routes of gene flow between populations, and geographic origins of parasites.

Key People

Assoc Prof Mayfong Mayxay
Head of Field Research
Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Vientiane, Lao PDR
Institute of Research and Education Development (IRED), University of Health Sciences, Ministry of Health, Vientiane, Lao PDR
Keobouphaphone Chindavongsa
Center of Malariology, Parasitology and Entomology (CMPE), Lao PDR